BCN Linkers
The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst. The ligation reaction is very fast and results in almost quantitative yield of stable triazoles. Within physiological temperature and pH ranges, the DBCO group does not react with amines or hydroxyls, which are naturally present in many biomolecules. Thus, DBCO has found broad application for studying dynamic biological systems such as live cells, whole organisms, and liv animals, ranging from visualizing protein expression, tracking protein localization, measuring protein activity and turnover, to nucleic acid immobilization and tracking, and lipid labeling in living cells and live animals.
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BCN Linkers
5-FAM-PEG3-BCN (exo)
$115.00 – $325.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
acid-PEG1-bis-PEG3-BCN (exo)
$380.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
Amino-bis-PEG3-BCN (exo)
$380.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
APN-BCN
$320.00 – $500.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
APN-PEG4-BCN(exo)
$280.00 – $430.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-alkyne (endo)
$350.00 – $780.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-amine (endo)
$320.00 – $780.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-amine (exo)
$240.00 – $680.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-Biotin (exo)
$240.00 – $620.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-C2-BCN (exo)
$290.00 – $780.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-NHS (exo)
$160.00 – $390.00 Select options This product has multiple variants. The options may be chosen on the product page -
BCN Linkers
BCN-PEG3-amine (endo)
$240.00 – $550.00 Select options This product has multiple variants. The options may be chosen on the product page
5-FAM-PEG3-BCN (exo)
Also known as 5-carboxyfluorescein-PEG3-BCN. A pegylated FAM dye with enhanced water solubility and containing a BCN moiety for click chemistry
acid-PEG1-bis-PEG3-BCN (exo)
A heterotrifunctional linker containing two BCN moieties for click chemistry and a carboxylic acid group
Amino-bis-PEG3-BCN (exo)
A heterotrifunctional linker containing two BCN moieties for click chemistry and a secondary amine
APN-BCN
A heterobifunctional linker containing a APN moiety with exquisite chemoselectivity for cysteine and a BCN moiety for click chemistry
BCN-alkyne (endo)
A heterobifunctional linker containing a BCN moiety and an alkyne for click chemistry with two azides sequentially
BCN-amine (endo)
A heterobifunctional linker containing a BCN moiety for click chemistry and a primary amine
BCN-amine (exo)
A heterobifunctional linker containing a BCN moiety and a primary amine
BCN-C2-BCN (exo)
A homobifunctional linker containing two BCN moieties for click chemistry
BCN-PEG3-amine (endo)
A heterobifunctional BCN linker with carboxylic acid reactivity