DBCO linkers

The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst. The ligation reaction is very fast and results in almost quantitative yield of stable triazoles. Within physiological temperature and pH ranges, the DBCO group does not react with amines or hydroxyls, which are naturally present in many biomolecules. Thus, DBCO has found broad application for studying dynamic biological systems such as live cells, whole organisms, and liv animals, ranging from visualizing protein expression, tracking protein localization, measuring protein activity and turnover, to nucleic acid immobilization and tracking, and lipid labeling in living cells and live animals.

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Product name
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CP-2020
CP-2022
CP-2023
CP-2024
CP-2025
CP-2026
CP-2027
CP-2028
CP-2030
CP-2031
CP-2032
CP-2033
CP-2034
CP-2035
CP-2036
CP-2037
CP-2038
CP-2039
CP-2040
CP-2042
CP-2043
DBCO-PEG3-TCO
CP-2044
CP-2047
CP-2067
CP-2070
CP-2079
CP-2084
CP-2089
CP-2092
CP-2093
CP-2094
CP-2098
CP-2099
CP-2100
CP-2102
CP-2110
CP-2111
CP-2121
CP-2215
CP-2216
CP-2230
CP-2235
CP-2237
CP-2242
CP-2260
CP-2261
CP-2262
CP-2268
CP-2269
CP-2270
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