DBCO linkers

The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst. The ligation reaction is very fast and results in almost quantitative yield of stable triazoles. Within physiological temperature and pH ranges, the DBCO group does not react with amines or hydroxyls, which are naturally present in many biomolecules. Thus, DBCO has found broad application for studying dynamic biological systems such as live cells, whole organisms, and liv animals, ranging from visualizing protein expression, tracking protein localization, measuring protein activity and turnover, to nucleic acid immobilization and tracking, and lipid labeling in living cells and live animals.

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Catalog #
Product name
Structure
Price
CP-2271
CP-2272
CP-2273
Mal-PEG2-tris-PEG3-DBCO
CP-2274
CP-4008
CP-4009
CP-4011
CP-4016
CP-4019
CP-5018
CP-5303
CP-6072
CP-6129
CP-6130
CP-6131
CP-6132
6132
CP-6139
CP-6140
CP-6141
CP-6142
CP-6143
CP-6144
CP-6145
CP-8009
CP-9012
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