Cysteine-selective APN and other Linkers
6-(2-(Methylsulfonyl)pyrimidin-5-yl)hex-5-ynoic acid
A heterobifunctional crosslinker with exquisite chemoselectivity for cysteine
6-(2-(Methylsulfonyl)pyrimidin-5-yl)hex-5-ynoic acid NHS ester
A heterobifunctional crosslinker with exquisite chemoselectivity for cysteine
APN-amine
Cysteine selective reagent. The resulting conjugate showes better aqueous stability than thiol-maleimide conjugate.
APN-BCN
A heterobifunctional linker containing a APN moiety with exquisite chemoselectivity for cysteine and a BCN moiety for click chemistry
APN-biotin
A biotinylation reagent containing a APN moiety with exquisite chemoselectivity for cysteine
APN-C4-amine.HCl
A heterobifunctional linker containing a APN moiety with exquisite chemoselectivity for cysteine and a primary amine group
APN-Mal
A heterobifunctional linker containing an APN moiety and a maleimide group for sequential conjugation with two sulfhydryls
APN-oxyamine.HCl
Superior to maleimides, cysteine-selective and aldehyde reactive crosslinker
APN-PEG4-azide
A heterobifunctional linker containing a APN moiety with exquisite chemoselectivity for cysteine and an azide group for click chemistry
APN-PEG4-PFP
A heterobifunctional crosslinker with exquisite chemoselectivity for cysteine