Specifications:
Chemical Formula: C7H7NO4
Molecular Weight: 169.14
CAS: 7423-55-4
Purity: >97%
Physical Form: white solid
Solubility: DCM, THF, DMF and DMSO
Storage at: 0-4 oC
3-Maleimidopropanoic acid can be used as a protein crosslinker or sulfhydryl (-SH) to carboxylic acid (-COOH) modification reagent. As a protein modifier. 3-Maleimidopropanoic acid is used to modify sulfhydryl groups at pH 6.5-7.5 to terminal carboxyl groups. 3-Maleimidopropanoic acid protein modification makes -COOH groups for subsequent coupling via EDC crosslinking. As a protein crosslinker, 3-Maleimidopropanoic acid can be used for the preparation of protein conjugates. The maleimide and carboxyl reactive groups of 3-Maleimidopropanoic acid crosslinker are reactive toward sulfhydryls and hydrazides/amines, respectively.