Specifications:
Chemical Formula:Â C11H12N2O4S
Molecular Weight: 268.29
CAS: 2356229-58-6
Purity: 97% by HPLC
Physical Form:
Solubility: THF, DCM, DMF and DMSO
Storage at: -20 oC
6-(2-(Methylsulfonyl)pyrimidin-5-yl)hex-5-ynoic acid is a heterobifunctional crosslinker containing an methylsulfonylpyridine moiety with exquisite chemoselectivity for cysteine and carboxylic acid. The superior stability of its cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.