Specifications:
Chemical Formula: C31H39N3O7
Molecular Weight: 565.66
CAS: N/A
Purity: >95%
Physical Form: oil
Solubility: DCM, THF, Acetonitrile, DMF and DMSO
Storage at: -20 oC
APN-PEG4-BCN (exo) is a heterobifunctional linker containing a BCN moiety for click chemistry and an APN group to react with free thiol .
BCN is ideally suited for aqueous bioconjugations due to its high reactivity with its azide counterpart combined with its high hydrophilicity, relative to all other metal-free click chemistry probes.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and BCN groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG4 Spacer – reduces aggregation, minimizes sterical hindrance, and enhances solubility