Specifications:
Chemical Formula: C22H37N3O7
Molecular Weight: 455.55
CAS: N/A
Purity: >90%
Physical Form: colorless oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -80 oC
BCN-PEG4-hydrazide (exo) is a heterobifunctional linker containing a BCN moiety for click chemistry and a hydrazide for hydrazone ligation.
BCN is ideally suited for aqueous bioconjugations due to its high reactivity with its azide counterpart combined with its high hydrophilicity, relative to all other metal-free click chemistry probes.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and BCN groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG4 Spacer – reduces aggregation, minimizes sterical hindrance, and enhances solubility