Specifications:
Chemical Formula: C25H21N3O4
Molecular Weight: 427.45
CAS: 1395786-30-7
Purity: >95%
Physical Form: white foam
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC
DBCO-Mal is a heterobifunctional linker containing a DBCO moiety for click chemistry and a maleimide group for sulfhydryl conjugation. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency