Specifications:
Chemical Formula: C53H73N3O16
Molecular Weight: 1008.16
CAS: N/A
Purity: >95%
Physical Form: light yellow oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC
DBCO-PEG12-aldehyde is heterobifunctional linker containing a DBCO moiety for click chemistry and a benzylaldehyde group for oxime/hydrazone ligation. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG12 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility