Specifications:
Chemical Formula: C30H34N2O6
Molecular Weight: 518.24
CAS: N/A
Purity: >95%
Physical Form: light yellow oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC
DBCO-PEG4-alkyne is a heterobifunctional linker containing a DBCO moiety and an alkyne group for sequential click chemistry with two different azides. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG4 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility