DBCO-PEG4-Maleimide

$179.00$460.00

A heterobifunctional bioorthogonal linker with azide (click reaction) and sulfhydryl reactivity

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Specifications:

Chemical Formula: C36H42N4O9
Molecular Weight: 674.74
CAS: 1480516-75-3
Purity: >95%
Physical Form: light yellow oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC

DBCO-PEG4-Maleimide is heterobifunctional linker containing a DBCO moiety for click chemistry and an maleimide group for sulfhydryl conjugation. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.

Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst

High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency

Hydrophilic PEG4 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility

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