DBCO-PEG5-DBCO

Specifications:

Chemical Formula: C₅₀H₅₄N₄O₉
Molecular Weight: 854.92
CAS: N/A
Purity: >95%
Physical Form: off-white solid
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC

DBCO-PEG5-DBCO is a homobifunctional linker containing two DBCO moieties for click chemistry. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.

Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst

High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency

Hydrophilic PEG5 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility