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DBCO-SS-NHS

$35.00$520.00

Also known as DBCO-CONH-S-S-COONHS Ester and DBCO-S-S-SE. A cleavable heterobifunctional linker containing a DBCO moiety for click chemistry and an activated NHS ester

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Specifications:

Chemical Formula: C28H27N3O6S2
Molecular Weight: 565.66
CAS: 1435934-53-4
Purity: >95%
Physical Form: white foam
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC

DBCO-SS-NHS is a cleavable heterobifunctional linker containing a DBCO moiety for click chemistry and an activated NHS ester. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.

Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst

High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency

Cleavable SS bond – can be reduced by free thiol molecules like DTT or GSH

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