DBCO-SS-PEG4-Biotin

Specifications:

Chemical Formula: C₄₄H₆₀N₆O₉S₃
Molecular Weight: 913.18
CAS: N/A
Purity: >95%
Physical Form: light yellow oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC

DBCO-SS-PEG4-Biotin is a cleavable biotinylation reagent containing a DBCO moiety for click chemistry and a disulfide bond. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.

Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst

High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency

Cleavable SS bond – can be reduced by free thiol molecules like DTT or GSH