Specifications:
Chemical Formula: C39H51N7O9
Molecular Weight: 761.86
CAS: N/A
Purity: >96%
Physical Form: white solid
Solubility: water, DMF and DMSO
Storage at: -20 oC
DOTA-C6-DBCO is a heterobifunctional chelating reagent containing a DBCO moiety for click chemistry and a DOTA as a chelating agent, especially for lanthanide ion. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency