Specifications:
Chemical Formula: C25H41N5O8
Molecular Weight: 539.62
CAS: N/A
Purity: >95%
Physical Form: white wax
Solubility: DCM, acetonitrile, DMF and DMSO
Storage at: -20 oC
Gly-Gly-Gly-PEG3-BCN (endo) is a heterobifunctional linker containing a BCN moiety for click chemistry and a terminal Gly-Gly-Gly sequence for sortase conjugation.
BCN is ideally suited for aqueous bioconjugations due to its high reactivity with its azide counterpart combined with its high hydrophilicity, relative to all other metal-free click chemistry probes.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and BCN groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG3 Spacer – reduces aggregation, minimizes sterical hindrance, and enhances solubility