Methylcyclopropene-PEG3-Mal

$250.00$460.00

A heterobifunctional MCP linker with sulfhydryl reactivity

SKU: CP-6135 Category: Tags: ,

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Specifications:

Chemical Formula: C21H31N3O8
Molecular Weight: 453.49
CAS: N/A
Purity: >90% by HPLC
Physical Form: colorless oil
Solubility: DCM, MeOH, DMF and DMSO
Storage at: -80 oC

Methylcyclopropene-PEG3-Mal is a heterobifunctional linker containing a methylcyclopropene moiety for inverse electron demand Diels-Alder cycloaddition reactions and a maleimide. The methylcyclopropene will react with tetrazine to yield a stable dihydropyridazine linkage.

Biocompatible – click reaction occurs efficiently under mild buffer conditions; requires no accessory reagents such as a copper catalyst or reducing agents (e.g. DTT)
Chemoselective – methylcyclopropenes do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic spacer – PEG3 spacer enhanced solubility in aqueous buffers

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