Also known as SATA, N-Succinimidyl-s-acetylthiopropionate is a sulfhydryl-addition reagent for covalent modification of primary amines to facilitate controlled, heterobifunctional crosslinking.
Specifications:
Chemical Formula: C9H11NO5S
Molecular Weight: 245.3
CAS: 84271-78-3
Purity: 98%
Physical Form: solid
Solubility: DCM, acetonitrile, DMF and DMSO
Storage at: -20 oC
Features of SATA:
• Adds a protected sulfhydryl that can be deprotected by hydroxylamine
• Allows long-term storage of the sulfhydryl-modified molecule
• Forms cleavable disulfide bonds with other sulfhydryl-containing molecules
• Reacts with primary amines (e.g., lysine residues proteins) to form stable amide bonds
• Preserves protein activity with its mild, non-denaturing reaction conditions