Specifications:
Chemical Formula: C32H48N2O8
Molecular Weight: 588.73
CAS: N/A
Purity: 95%
Physical Form: oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -80 oC
PEG4-bis-BCN (endo) is a h0mobifunctional linker containing two BCN moieties for click chemistry . The BCN demonstrates high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst with least hydrophobicity among all cyclooctynes.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and BCN groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG4 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility