UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. UNC10217938A enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes. UNC10217938A also enhances the effects of antisense and siRNA oligonucleotides.
Specifications:
Chemical Formula: C₂₆H₂₈N₆O₂
Molecular Weight: 456.54
CAS: 1347749-97-6
Purity: >97%
Physical Form: solid
Solubility: MeOH, DMF and DMSO
Storage at: -20 oC
Reference:
[1]. Yang B, et al. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucleic Acids Res. 2015 Feb 27;43(4):1987-96.